Historically significant events in the discovery of RANK/RANKL/OPG

doi:10.5312/wjo.v4.i4.186

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Oct 18, 2013 (publication date) through Nov 22, 2024

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Orthop. Oct 18, 2013; 4(4): 186-197
Published online Oct 18, 2013. doi: 10.5312/wjo.v4.i4.186

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Figure 4 Concepts of regulation of osteoclastogenesis from the mid-1980’s until the discovery of the molecular regulation mechanisms. Three different signaling pathways converged to promote formation of osteoclasts through undefined mechanisms. IL: Interleukin; PTH: Parathyroid hormone; LIF: Leukemia inhibitory factor.

Citation: Martin TJ. Historically significant events in the discovery of RANK/RANKL/OPG. World J Orthop 2013; 4(4): 186-197
URL: https://www.wjgnet.com/2218-5836/full/v4/i4/186.htm
DOI: https://dx.doi.org/10.5312/wjo.v4.i4.186