Osteoclast fusion and regulation by RANKL-dependent and independent factors

doi:10.5312/wjo.v3.i12.212

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Dec 18, 2012 (publication date) through Nov 15, 2024

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Orthop. Dec 18, 2012; 3(12): 212-222
Published online Dec 18, 2012. doi: 10.5312/wjo.v3.i12.212

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Figure 2 Increased osteoclast fusion in cells from TRAF3f/f; CSK-Cre mice. Bone marrow mono-nuclear cells from control mice (TRAF3f/f) and TRAF3f/f; CSK-Cre mice were cultured with M-CSF for 2 d and then treated with RANKL for additional 2 d. Photos show multi-nuclear mature osteoclasts (arrows) in cells from TRAF3f/f; CSK-Cre mice. TNF: Tumor necrosis factor; TRAF: TNF receptor-associated factors; M-CSF: Macrophage colony-stimulating factor.

Citation: Xing L, Xiu Y, Boyce BF. Osteoclast fusion and regulation by RANKL-dependent and independent factors. World J Orthop 2012; 3(12): 212-222
URL: https://www.wjgnet.com/2218-5836/full/v3/i12/212.htm
DOI: https://dx.doi.org/10.5312/wjo.v3.i12.212