Denosumab regimens in the treatment of giant cell tumor of bone: A systematic review with meta-analysis

Table 1 Database search strategy

Databases	Strategy
MEDLINE via PubMed	1 "Giant Cell Tumor of Bone"[Mesh] OR osteoclastoma; 2 "Denosumab"[Mesh] OR (Xgeva) OR (AMG 162) OR (Prolia); 3 1 AND 2
SciELO	1 "Giant Cell Tumor of Bone" OR "Tumor Óseo de Células Gigantes" OR "Tumor de Células Gigantes do Osso" OR Osteoblastoma; 2 Denosumab OR Xgeva OR AMG 162 OR Prolia OR Denosumabe; 3 1 AND 2
EMBASE	1 'osteoclastoma'/exp OR (giant AND cell AND tumor AND of AND bone) OR (giant AND cell AND tumor, AND bone) OR (giant AND cell AND tumour AND of AND bone) OR (giant AND cell AND tumour, AND bone) OR (polyostotic AND osteoclastoma); 2 'denosumab'/exp OR (amg AND 162) OR amg162 OR amgiva OR prolia OR xgeva; 3 1 AND 2
ScienceDirect	1 ("Giant Cell Tumor of Bone" OR osteoclastoma) AND (Denosumab OR Xgeva OR AMG 162 OR Prolia)
Cochrane Library	1 MeSH descriptor: [Giant Cell Tumor of Bone] explode all trees; 2 osteoclastoma; 3 1 OR 2; 4 MeSH descriptor: [Denosumab] explode all trees; 5 Xgeva; 6 AMG 162; 7 Prolia; 8-4 OR 5 OR 6 OR 7; 6-3 AND 8
Clinicaltrials.gov	1 (Giant Cell Tumor of Bone OR osteoclastoma) AND (Denosumab OR Xgeva OR AMG 162 OR Prolia)
Registro Brasileiro de Ensaios Clínicos	1 (Giant Cell Tumor of Bone OR osteoclastoma) AND (Denosumab OR Xgeva OR AMG 162 OR Prolia)
Open Access Theses and Dissertations	1 ("Giant Cell Tumor of Bone" OR osteoclastoma) AND (Denosumab OR Xgeva OR AMG 162 OR Prolia)
Biblioteca Digital Brasileira de Teses e Dissertações	1 ("Giant Cell Tumor of Bone" OR osteoclastoma) AND (Denosumab OR Xgeva OR AMG 162 OR Prolia)