Impacts of mesenchymal stem cells and hyaluronic acid on inflammatory indicators and antioxidant defense in experimental ankle osteoarthritis

doi:10.5312/wjo.v15.i11.1056

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Nov 18, 2024 (publication date) through Nov 15, 2024

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Orthop. Nov 18, 2024; 15(11): 1056-1074
Published online Nov 18, 2024. doi: 10.5312/wjo.v15.i11.1056

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Figure 5 Histopathological evaluation of treatments on monosodium iodate-induced osteoarthritis in rat. A and B: Microphotographs showing the histological changes in hind ankle of normal control (photomicrographs); C and D: Osteoarthritic control rats (photomicrographs) in Hematoxylin and eosin (100 ×) stained sections. The integral histological architecture of hind ankle joints was found in normal control rats. Osteoarthritic control rats showed synovial hyperplasia, mononuclear inflammatory cell infiltration, marked pannus formation, cartilage destruction and bone erosion. CA: Articular cartilage; EC: Erosion of cartilage; IF: Inflammatory cells infiltration; PF: Pannus formation; SF: Synovial fluid; SM: Synovial membrane; SP: Spongy bone.

Citation: Hagag UI, Halfaya FM, Al-Muzafar HM, Al-Jameel SS, Amin KA, Abou El-Kheir W, Mahdi EA, Hassan GANR, Ahmed OM. Impacts of mesenchymal stem cells and hyaluronic acid on inflammatory indicators and antioxidant defense in experimental ankle osteoarthritis. World J Orthop 2024; 15(11): 1056-1074
URL: https://www.wjgnet.com/2218-5836/full/v15/i11/1056.htm
DOI: https://dx.doi.org/10.5312/wjo.v15.i11.1056