Chondroitin sulfate and glucosamine combination in patients with knee and hip osteoarthritis: A long-term observational study in Russia

doi:10.5312/wjo.v14.i6.443

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World Journal of Orthopedics

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World J Orthop. Jun 18, 2023; 14(6): 443-457
Published online Jun 18, 2023. doi: 10.5312/wjo.v14.i6.443

Table 3 Change in Hip disability and Osteoarthritis Outcome Score subscale scores (Full analysis set)

Subscale	Hip osteoarthritis (n = 278) – HOOS scale					P value^a
Subscale	Visit 1, baseline, n = 278	Visit 2, week 16-24, n = 272	Visit 3, week 36-44, n = 271	Visit 4, week 56-64, n = 270	Changes from baseline on visit 4	P value^a
Pain	60.97 (58.93-63.02)	76.36 (74.34-78.38)	80.89 (78.95-82.84)	83.63 (81.64-85.62)	22.81 (20.47-25.16)	< 0.001
Symptoms	61.17 (59.08-63.26)	73.73 (71.62-75.84)	78.17 (76.21-80.14)	81.19 (79.21-83.16)	19.93 (17.49-22.36)	< 0.001
Functional activity of the joint	65.57 (63.62-67.52)	78.46 (76.72-80.21)	81.59 (79.93-83.26)	84.11 (82.45-85.76)	18.77 (16.61-20.93)	< 0.001
Quality of life	46.79 (44.72-48.85)	60.75 (58.50-63.01)	65.41 (63.09-67.72)	69.33 (66.83-71.82)	22.71 (20.14-25.28)	< 0.001

^awith Holm-Bonferroni method. Mean data are presented (95%CI). CI: confidence interval; HOOS: Hip disability and Osteoarthritis Outcome Score (HOOS).

Citation: Lila AM, Alekseeva LI, Baranov AA, Taskina EA, Kashevarova NG, Lapkina NA, Trofimov EA. Chondroitin sulfate and glucosamine combination in patients with knee and hip osteoarthritis: A long-term observational study in Russia. World J Orthop 2023; 14(6): 443-457
URL: https://www.wjgnet.com/2218-5836/full/v14/i6/443.htm
DOI: https://dx.doi.org/10.5312/wjo.v14.i6.443