Chondroitin sulfate and glucosamine combination in patients with knee and hip osteoarthritis: A long-term observational study in Russia

doi:10.5312/wjo.v14.i6.443

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Jun 18, 2023 (publication date) through Oct 2, 2024

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World Journal of Orthopedics

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2218-5836

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World J Orthop. Jun 18, 2023; 14(6): 443-457
Published online Jun 18, 2023. doi: 10.5312/wjo.v14.i6.443

Table 2 Change in Knee Injury and Osteoarthritis Outcome Score subscale scores (Full analysis set)

Subscale	Knee osteoarthritis (n = 824) – KOOS scale					P value^a
Subscale	Visit 1, baseline, n = 824	Visit 2, week 16-24, n = 798	Visit 3 week 36-44, n = 794	Visit 4, week 56-64, n = 794	Changes from baseline on visit 4	P value^a
Pain	61.48 (60.36-62.61)	79.59 (78.48-80.70)	82.50 (81.45-83.56)	84.24 (83.15-85.34)	22.87 (21.56-24.18)	< 0.001
Symptoms	62.25 (61.02-63.48)	77.65 (76.46-78.84)	81.09 (79.97-82.21)	82.80 (81.66-83.93)	20.78 (19.43-22.13)	< 0.001
Functional activity of the joint	61.46 (60.73-62.18)	72.48 (71.63-73.34)	75.78 (74.86-76.69)	78.03 (77.06-78.99)	16.60 (15.59-17.61)	< 0.001
Quality of life	44.99 (43.83-46.16)	61.40 (60.10-62.69)	65.91 (64.54-67.27)	69.92 (68.45-71.39)	24.87 (23.41-26.34)	< 0.001

^awith Holm-Bonferroni method. Mean data are presented (95%CI). CI: Confidence interval; KOOS: Knee Injury and Osteoarthritis Outcome Score.

Citation: Lila AM, Alekseeva LI, Baranov AA, Taskina EA, Kashevarova NG, Lapkina NA, Trofimov EA. Chondroitin sulfate and glucosamine combination in patients with knee and hip osteoarthritis: A long-term observational study in Russia. World J Orthop 2023; 14(6): 443-457
URL: https://www.wjgnet.com/2218-5836/full/v14/i6/443.htm
DOI: https://dx.doi.org/10.5312/wjo.v14.i6.443