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©The Author(s) 2023.
World J Orthop. Jun 18, 2023; 14(6): 411-426
Published online Jun 18, 2023. doi: 10.5312/wjo.v14.i6.411
Published online Jun 18, 2023. doi: 10.5312/wjo.v14.i6.411
Table 1 Summary demographics, and radiographic and operative details for patients with Duchenne muscular dystrophy and spinal deformity treated by posterior instrumented spinal fusion (mean ± SD)
| Parameter (units) | Patient cohort |
| Number of patients (n) | 43 |
| Clinical/operative | |
| Age at surgery (yr) | 14.4 (± 1.6; 10.8-18.2) |
| Spinal deformity, n (%) | |
| Scoliosis | 33 (76.7) |
| Kyphoscoliosis | 10 (23.3) |
| Single thoracolumbar curve | 40 (93) |
| Double thoracic and lumbar curve | 3 (7) |
| Gastrostomy for nutrition pre-operatively, n (%) | 4 (9.3) |
| NIV pre-operatively, n (%) | 5 (11.6) |
| Moderate left ventricular systolic dysfunction, n (%) | 2 (4.6) |
| Operative time (minutes) | 352.1 (± 72.7; 150-490) |
| Intraoperative blood loss (%; TBV) | 36 (± 23.5; 12-150) |
| Distal fusion extent, n (%) | |
| L4 | 4 (9.3) |
| L5 | 21 (48.8) |
| Pelvis | 18 (41.9) |
| Length of stay in ICU (days) | 6.5 (± 3.1; 3-17) |
| Length of stay in hospital (days) | 14.1 (± 7.2; 7-30) |
| Postoperative complications, n (%) | 11 (25.6) |
| Early wound infections | 4 (9.3) |
| Removal of instrumentation (pelvic fixation) | 1 (2.3) |
| Hepatotoxicity | 4 (9.3) |
| Pneumonia | 2 (4.6) |
| Preoperative radiographs | |
| Scoliosis (Cobb angle; o) | 57.5 (± 31; 10-120) |
| Scoliosis on traction radiographs (o) | 32 (± 24; 0-92) |
| Scoliosis flexibility index (%) | 52 (± 27.5; 7-100) |
| Pelvic obliquity (o) | 16.3 (± 13.2; 0-46) |
| Pelvic obliquity on traction radiographs (o) | 9.2 (± 9.3; 0-35) |
| Pelvic obliquity flexibility index (%) | 58 (± 31; 0-100) |
| Thoracic kyphosis (T5-T12; o) | 55.8 (± 28.1; 0-98) |
| Lumbar lordosis (T12-S1; o) | 11.1 (± 20.3; 0-79) |
| Coronal balance (C7PL, cm) | 3.8 (± 2.7; 0-12) |
| Sagittal balance (C7PL, cm) | 6.1 (± 6.4; -11.4-1) |
| Postoperative radiographs | |
| Scoliosis (Cobb angle; o) | 15.6 (± 16.4; 0-60) |
| Scoliosis correction (%) | 79.2 (± 18.6; 40-100) |
| Pelvic obliquity (o) | 4.6 (± 6.4; 0-23) |
| Pelvic obliquity correction (%) | 80.8 (± 25; 19-100) |
| Thoracic kyphosis (T5-T12; o) | 33.7 (± 7.3; 20-55) |
| Lumbar lordosis (T12-S1; o) | 35.8 (± 8.7; 20-55) |
| Coronal balance (C7PL, cm) | 0.68 (± 1.1; 0-4.5) |
| Sagittal balance (C7PL, cm) | -0.18 (± 1.6; -4 to 5.4) |
- Citation: Roberts S, Arshad A, Tsirikos AI. Surgical and long-term functional outcomes of patients with Duchenne muscular dystrophy following spinal deformity correction. World J Orthop 2023; 14(6): 411-426
- URL: https://www.wjgnet.com/2218-5836/full/v14/i6/411.htm
- DOI: https://dx.doi.org/10.5312/wjo.v14.i6.411