Fragility of statistically significant findings from randomized clinical trials of surgical treatment of humeral shaft fractures: A systematic review

Table 4 Summary of outcomes with reported differences between groups

Continuous variable	Superior treatment	Inferior treatment	First author (last name)
Time to union	IMN	ORPO	Changulani
Time to union	IMN	ORPO	Fan
Operative time	IMN	ORPO	Fan
Operative time	IMN	ORPO	Wali
Operative time	MIPO	IMN	Lian
Operative time	MIPO	ORPO	Hadhoud
Intraoperative blood loss	IMN	ORPO	Fan
Intraoperative blood loss	IMN	ORPO	Wali
Intraoperative blood loss	MIPO	IMN	Lian
Hospital stay	IMN	ORPO	Fan
Hospital stay	IMN	ORPO	Wali
Constant scores	MIPO	IMN	Li
Rodriguez-Merchan criteria	DCP	IMN	Singisetti
Shoulder ROM	MIPO	IMN	Li
Shoulder ROM	DCP	IMN	Chapman
Elbow ROM	IMN	DCP	Chapman

ORPO: Open reduction and plate osteosynthesis; DCP: Dynamic compression plate; LCP: Locking compression plate; IMN: Intramedullary nail; MIPO: Minimally invasive plate osteosynthesis.