Performance of alpha-defensin lateral flow test after synovial fluid centrifugation for diagnosis of periprosthetic knee infection

Table 1 Inclusion and exclusion criteria of the study

Inclusion criteria	Exclusion criteria
Any of the following suspicious signs or symptoms of chronic knee PJI (more than 90 d), as following:	Acute signs or symptoms of knee infection (less than 90 d)
Persistent knee pain (more than 3 mo), without other apparent cause
Persistent joint effusion (more than 3 mo)
Persistent local heat (more than 3 mo)
Presence of draining sinus
Early failure of the prosthesis (less than 5 yr)
Radiographic findings suggesting infection[33]
Have not used antibiotics for at least 4 wk before the evaluation	Insufficient synovial fluid volume during knee aspiration
	Insufficient data for fulfilling the periprosthesis infection criteria[11]

PJI: Periprosthetic joint infection.