Dual antibiotic loaded bone cement in patients at high infection risks in arthroplasty: Rationale of use for prophylaxis and scientific evidence

Figure 3 Overview of published clinical study results comparing prosthetic joint infection rate in patients in single low dose cement and dual high dose cement group across different indications. The table below lists the main study authors, indication and study design, number of patients included, evidence level of clinical study and prosthetic joint infection rate in % in both study groups. PJI: Prosthetic joint infection; SLDC: Single low dose cement = PALACOS R+G (containing 0.5 g of gentamicin); DHDC: Dual high dose cement = COPAL G+C (gentamicin + clindamycin); FNF: Femoral neck fracture; rTKA: Revision total knee arthroplasty; RFI: Risk for infection; THA: Total hip arthroplasty.