Systematic review of single stage revision for prosthetic joint infection

Table 3 International Consensus Meeting 2018 Guidelines for prosthetic joint infection for hip and knee arthroplasty

Major criteria
Two positive cultures of the same organism / Sinus tract with communication to the joint or prosthesis
Minor criteria
Criteria	Acute threshold	Chronic threshold	Score
CRP (mg/L) or D Dimer (ug/L)	100; unknown	10; 860	2
ESR (mm/h)	No role	30	1
Synovial WBC or leukocyte esterase or alpha defensin	10000; ++; 1.0	3000; ++; 1.0	2
Synovial PMN %	90	70	2
Single positive culture			2
Positive histology			3
Positive intraoperative purulence			3

A positive prosthetic joint infection is one of two major criteria, or 6 or more points for minor criteria. 3-5 points for minor criteria is inconclusive and less than 3 points is negative for prosthetic joint infection. WBC: White blood cell; PJI: Prosthetic joint infection; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; PMN: Polymorphonuclearleukocyte.