Good accuracy of the alpha-defensin lateral flow test for hip periprosthetic joint infection: A pilot study in a retrospective cohort of 52 patients

doi:10.5312/wjo.v11.i1.36

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 11, Issue 1

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (7445)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-1) series, Tables (1-8) series.

Item

Count

PDF

333

WORD

169

HTML

3574

Figures (1-1)

458

Tables (1-8)

507

Sum=5041

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

949

Download

1455

Sum=2404

Jan 18, 2020 (publication date) through Jan 26, 2025

Times Cited of This Article

Times Cited (4)

Journal Information of This Article

Publication Name

World Journal of Orthopedics

ISSN

2218-5836

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Orthop. Jan 18, 2020; 11(1): 36-46
Published online Jan 18, 2020. doi: 10.5312/wjo.v11.i1.36

Table 7 Characteristics of all patients with positive alpha-defensin lateral flow test and/or positive or inconclusive criteria

*Case*	*Criteria*	A	B	C	D	E	F	G	H	I	PJI?
*Case*	Art	Sinus tract	Visible purulence	CRP (mg/ L)	ESR (mm/h)	WBC count (cells/μL)	PMN%	Culture synovial fluid (nr of cultures)	Culture tissue (nr of cultures)	AD	MSIS (+/-; criteria)		EBJIS (+/-; criteria)		2018 ICM (+/-/i; criteria)		Revision surgery	1- or 2-stage
1	CoC	-	-	6.5	21.0	19100	91	neg (1)	neg (6)	+	-	E,F	+	E,F	+	E,F,I	Yes	2-stage
2	MoP	Yes	-	9.0	23.0	-	-	pos (2)	pos (8/9)	+	+	A,G,H	+	A,G,H	+	A,G,H,I	Yes	2-stage
3	MoP	-	-	8.5	29.0	3000	4	neg (2)	-	-	-		+	E	-		No	-
4	MoP	-	-	9.8	16.0	6200	77	neg (2)	pos (5/8)	+	+	E,H	+	E,F,H	+	E,H,I	Yes	2-stage
5	CoC	-	-	6.9	10.0	2300	-	neg (1)	-	-	-		+	E	-		No	-
6	MoP	-	-	12.0	26.0	10	-	neg (2)	pos (1/2)	-	-	C,H	-		i	C,H	Yes	1-stage
7	MoP	-	-	-	-	9350	-	neg (1)	-	-	-	E	+	E	-	E	No	-
8	HA	-	-	-	-	-	-	neg (1)	pos (1/6)	+	-	H	-		i	H,I	Yes	1-stage
9	MoP	-	-	144.0	64.0	37300	92	pos (1/2)	pos (2/6)	+	+	C,D,E,F,G,H	+	E,F,G,H	+	C,D,E,F,H,I	Yes	DAIR
10	MoP	-	-	61.0	72.0	7900	95	pos (1/1)	pos (9/9)	+	+	C,D,E,F,G,H	+	E,F,G,H	+	C,D,E,F,H,I	Yes	2-stage
11	MoP	-	-	71.0	55.0	35300	97	pos (2/2)	pos (7/7)	+	+	C,D,E,F,G,H	+	E,F,G,H	+	C,D,E,F,H,I	Yes	2-stage
12	HA	-	-	9.6	-	4900	81	-	-	+	-	E,F	+	E,F	+	E,F,I	No	-
13	MoM	-	Yes	195.0	-	264000	96	neg (2)	-	+	+	B,C,E,F	+	B,E,F	+	B,C,E,F,I	No	-
14	MoP	-	-	15.0	13.0	8000	-	neg (1)	neg (6)	+	-	C,E	+	E	+	C,E,I	Yes	2-stage
15	HA	-	-	1.0	9.0	4000	15	neg (2)	-	-	-	E	+	E	-	E	No	-
16	MoM	-	-	5.7	8.0	5170	52	neg (3)	-	+	-	E	+	E	+	E,I	No	-

Art: Articulation; CoC: Ceramic on ceramic; MoP: Metal on polyethylene; MoM: Metal on metal; HA: Hemiarthroplasty; CoP: Ceramic on polyethylene; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; WBC: White blood cell; PMN%: Polymorphonuclear neutrophil percentage; PJI: Prosthetic joint infection; AD: Alpha-defensin test; MSIS: Musculoskeletal Infection Society; EBJIS: The European Bone and Joint Infection Society; i: Inconclusive; +: Positive; -: Negative.

Citation: Kuiper JW, Pander P, Vos SJ. Good accuracy of the alpha-defensin lateral flow test for hip periprosthetic joint infection: A pilot study in a retrospective cohort of 52 patients. World J Orthop 2020; 11(1): 36-46
URL: https://www.wjgnet.com/2218-5836/full/v11/i1/36.htm
DOI: https://dx.doi.org/10.5312/wjo.v11.i1.36