Good accuracy of the alpha-defensin lateral flow test for hip periprosthetic joint infection: A pilot study in a retrospective cohort of 52 patients

Table 2 European Bone and Joint Infection Society criteria for periprosthetic joint infection definition. One or more criteria fulfilled means positive periprosthetic joint infection diagnosis[4]

Sinus tract OR purulence around the prosthesis;

Acute inflammation on histopathology of periprosthetic tissue;

Elevated synovial fluid white blood cell count of more than 2.000 cells/μL OR elevated synovial fluid polymorphonuclear neutrophil percentage (PMN%) > 70%;

Microbial growth in synovial fluid OR > 2 tissue samples (for highly virulent microorganisms already one positive sample confirms infection) OR sonication fluid (≥ 50 CFU/mL).