Yttrium-90 microsphere selective internal radiation therapy for liver metastases following systemic chemotherapy and surgical resection for metastatic adrenocortical carcinoma

Figure 1 Tissue histopathology of a hepatic lesion confirms metastatic adrenocortical carcinoma. Hematoxylin and eosin (HE) staining (A) at 200 × magnification of tissue from the hepatic mass shows diffuse infiltrating cords of cells with hyperchromasia, eosinophilic cytoplasm, and a mild degree of nuclear pleomorphism in a background of myxoid stroma. Additional positive immunostaining with inhibin (B) and melan-A (C) at 40 × magnification as well as CKAE1/3 (D) at 100 × magnification confirms the diagnosis as adrenocortical carcinoma.