Copyright
©The Author(s) 2017.
World J Clin Oncol. Oct 10, 2017; 8(5): 412-419
Published online Oct 10, 2017. doi: 10.5306/wjco.v8.i5.412
Published online Oct 10, 2017. doi: 10.5306/wjco.v8.i5.412
Table 3 Univariate and multivariate analyses of different prognostic factors for overall survival
Variable | Modality | n | Univariate | Multivariate | ||
5-yr OS (%) | P value | HR (95%CI) | P value | |||
Age (yr) | < 65 | 32 | 27.9 | 0.095 | 1 | |
≥ 65 | 18 | 14.8 | 1.5 (0.8–3.0) | 0.197 | ||
Sex | Male | 43 | 19.8 | 0.618 | ||
Female | 7 | 42.9 | ||||
Preoperative CEA level (ng/mL) | < 20 | 21 | 23.7 | 0.671 | ||
≥ 20 | 29 | 22.9 | ||||
Tumor size (mm) | < 60 | 15 | 29.6 | 0.634 | ||
≥ 60 | 35 | 20.9 | ||||
T category | T2, 3 | 25 | 17.3 | 0.515 | ||
T4 | 25 | 32.5 | ||||
Histopathological grading | G1, 2 | 36 | 25 | 0.348 | ||
G3 | 14 | 21.4 | ||||
Lymphatic invasion | Absence | 6 | 0 | 0.446 | ||
Presence | 44 | 24.2 | ||||
Venous invasion | Absence | 10 | 40 | 0.215 | ||
Presence | 40 | 19.1 | ||||
Lymph node metastasis | Absence | 9 | 0 | 0.904 | ||
Presence | 41 | 27.5 | ||||
LPLND | Absence | 23 | 17 | 0.523 | ||
Presence | 27 | 28.7 | ||||
No. of metastatic organs | 1 | 44 | 23.8 | 0.866 | ||
2 | 6 | 22.2 | ||||
Metastatic organ | Liver only | 25 | 36 | 0.241 | ||
Others | 25 | 10.6 | ||||
Grade ≥ 3 complication of primary tumor resection | Absence | 38 | 28.8 | 0.398 | ||
Presence | 12 | 9.5 | ||||
Residual tumor status | R0 | 20 | 59 | < 0.001 | 1 | |
R2 | 30 | 3.6 | 2.1 (1.4–3.0) | < 0.001 | ||
Preoperative chemotherapy | Absence | 41 | 17.6 | 0.254 | ||
Presence | 9 | 55.6 | ||||
Postoperative chemotherapy | Absence | 7 | 38.1 | 0.397 | ||
Presence | 43 | 24.3 |
- Citation: Tamura H, Shimada Y, Kameyama H, Yagi R, Tajima Y, Okamura T, Nakano M, Nakano M, Nagahashi M, Sakata J, Kobayashi T, Kosugi SI, Nogami H, Maruyama S, Takii Y, Wakai T. Prophylactic lateral pelvic lymph node dissection in stage IV low rectal cancer. World J Clin Oncol 2017; 8(5): 412-419
- URL: https://www.wjgnet.com/2218-4333/full/v8/i5/412.htm
- DOI: https://dx.doi.org/10.5306/wjco.v8.i5.412