Current state and controversies in fertility preservation in women with breast cancer

doi:10.5306/wjco.v8.i3.241

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Jun 10, 2017; 8(3): 241-248
Published online Jun 10, 2017. doi: 10.5306/wjco.v8.i3.241

Table 2 Common adjuvant chemotherapy regimens for breast cancer and their impact of fertility

Chemotherapy regimen	Risk of amenorrhea or infertility
Chemotherapy regimen	Age ≤ 35 yr	Age >35 yr
CMF	4%-40%	80%-100%
CEF	47%	80%-100%
CAF	No data	30%
AC	13.90%	68.20%
AC-T	9%-13%	65%-67%
AC-TH	0-14%	56%-67%

A: Doxorubicin; C: Cyclophosphamide; E: Epirubicin; F: 5-Fluorouracil; H: Trastuzumab; M: Methotrexate; T: Paclitaxel.

Citation: Taylan E, Oktay KH. Current state and controversies in fertility preservation in women with breast cancer. World J Clin Oncol 2017; 8(3): 241-248
URL: https://www.wjgnet.com/2218-4333/full/v8/i3/241.htm
DOI: https://dx.doi.org/10.5306/wjco.v8.i3.241