Study of recombinant human interleukin-12 for treatment of complications after radiotherapy for tumor patients

Table 2 Results of immunologic detection for the treatment group and the control group (mean ± SD, n = 10)

Group	Indicator	0 d	12 h	3 d	7 d	14 d	21 d	28 d
Control	CD4/8	20.4 ± 2.6	18 ± 1.2	17.5 ± 1.2	17.8 ± 1.3	18.4 ± 1.2	17.3 ± 1.4	16.5 ± 0.4
	CD45	75.2 ± 7.5	68.1 ± 5.2	65.4 ± 4.2	83.3 ± 5.2	79.3 ± 3.7	62.4 ± 5.1	60.3 ± 3.6
	CD56	12.3 ± 1.2	8.7 ± 0.6	7.6 ± 0.5	11.4 ± 1.3	10.4 ± 0.9	8.2 ± 0.6	6.7 ± 0.5
50 ng/kg	CD4/8	28.2 ± 1.8	22.4 ± 1.6	19.8 ± 1.6	19.6 ± 1.6	21.4 ± 1.8	18.8 ± 1.2	16.9 ± 1.4
	CD45	81.9 ± 2.4	78.8 ± 5.1	75.2 ± 3.6	82.9 ± 3.8	79.8 ± 5.6	62.4 ± 4.6	51.8 ± 4.3
	CD56	27.9 ± 2.2	21.9 ± 1.8	19.2 ± 1.2	22.1 ± 1.8	19.7 ± 2.1	21.6 ± 1.3	22.4 ± 0.9
100 ng/kg	CD4/8	15.4 ± 1.5	12.7 ± 1.2	11.5 ± 1.1	10.6 ± 1.2	10.1 ± 0.3	9.2 ± 0.4	8.7 ± 0.2
	CD45	84.3 ± 2.6	66.1 ± 3.8	68.7 ± 3.5	67.9 ± 4.4	57.6 ± 4.6	63.1 ± 3.6	70.2 ± 3.1
	CD56	14.8 ± 1.8	8.9 ± 0.6	10.8 ± 0.9	12.3 ± 1.5	10.4 ± 4.6	12.9 ± 0.3	11.6 ± 0.4
150 ng/kg	CD4/8	16.5 ± 1.2	12.8 ± 1.2	11.6 ± 0.9	13.1 ± 4.6	12.6 ± 1.5	10.8 ± 0.9	7.6 ± 0.5
	CD45	74.2 ± 3.6	63.2 ± 3.2	66.1 ± 4.8	82.7 ± 5.2	68.1 ± 4.6	75.2 ± 4.2	65.1 ± 4.1
	CD56	6.2 ± 0.3	6.5 ± 0.3	5.9 ± 0.3	7.9 ± 0.6	8.2 ± 7.4	8.8 ± 0.9	6.5 ± 0.1
200 ng/kg	CD4/8	9.6 ± 0.4	8.3 ± 0.61	7.6 ± 0.6	7.2 ± 0.9	8.6 ± 4.6	8.2 ± 1.2	6.1 ± 0.2
	CD45	64.5 ± 4.2	60.7 ± 4.2	65.8 ± 4.4	76.6 ± 5.9	74.3 ± 4.6	73.2 ± 5.2	55.9 ± 5.0
	CD56	3.8 ± 0.2	2.8 ± 0.2	4.4 ± 0.4	4.9 ± 0.9	6.2 ± 0.6	5.9 ± 0.3	4.5 ± 0.1
250 ng/kg	CD4/8	6.4 ± 0.2	5.7 ± 0.2	4.2 ± 0.3	4.7 ± 0.3	3.5 ± 0.3	3.4 ± 0.9	3.1 ± 0.9
	CD45	46.5 ± 3.9	40.2 ± 3.2	57.9 ± 4.1	66.5 ± 3.8	54.9 ± 4.2	50.4 ± 4.9	35.9 ± 3.2
	CD56	4.3 ± 0.2	3.9 ± 0.2	5.4 ± 0.4	6.3 ± 0.5	6.6 ± 0.3	7.2 ± 0.6	6.4 ± 0.8