Bethesda System for Reporting Thyroid Cytopathology: A three-year study at a tertiary care referral center in Saudi Arabia

Table 4 Comparison rates of malignancy (%) on surgical resection for fine-needle aspiration diagnostic categories and malignancy risk of recent studies

	Published year	Comparison of diagnostic categories
		I (ND)	II (Benign)	III (AUS/FLUS)	IV (FN/SFN)	V (SM)	VI (malignant)
Recent studies
Park et al[22]	2014	13.3	40.6	9.1	0.4	19.3	17.6
Mondal et al[10]	2013	1.2	87.5	1	4.2	1.4	4.7
Mufti et al[29]	2012	11.6	77.6	0.8	4	2.4	3.6
Wu et al[30]	2012	20.1	39	27.2	8.4	2.6	2.7
Bongiovanni et al[31]	2012	2	54.7	6.3	25.3	6.3	5.4
Present study		3.2	75.3	9.1	5	2.2	5.1
Comparison of malignancy risk
Haugen et al[32] (meta-analysis)	2016	9-32	1-10	6-48	14-34	53-97	94-100
Pantola et al[33] 2016	2016	0	0	8.3	10	100	100
Park et al[22]	2014	35.3	5.6	69	50	38.7	98.9
Mondal et al[10]	2013	0	4.5	20	30.6	75	97.8
Mufti et al[29]	2012	20	3.1	50	20	80	100
Wu et al[30]	2012	12	8	27	33	68	100
Present study		25	8.9	14.3	47.2	69.3	96.7

ND: Nondiagnostic; AUS/FLUS: Atypia of undetermined significance/follicular lesion of undetermined significance; FN/SFN: Follicular neoplasm/suspicious for follicular neoplasm; SM: Suspicious for malignancy.