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©The Author(s) 2016.
World J Clin Oncol. Oct 10, 2016; 7(5): 395-405
Published online Oct 10, 2016. doi: 10.5306/wjco.v7.i5.395
Published online Oct 10, 2016. doi: 10.5306/wjco.v7.i5.395
Table 3 Association between tobacco, dietary habits, xenobiotic metabolizing genes polymorphisms, and oncohematological diseases n (%)
| Cases n = 125 | Controls n =310 | OR (95%CI) | P | |
| Tobacco smoking status | ||||
| Never | 49 (39.8) | 142 (46.4) | Ref. | |
| Former | 47 (38.2) | 100 (32.7) | 1.36 (0.84-2.19) | 0.202 |
| Current | 27 (22) | 64 (20.9) | 1.22 (0.70-2.13) | 0.478 |
| Consumption of canned food | ||||
| 0-2 times/wk | 121 (96.8) | 292 (94.8) | Ref. | 0.370 |
| 3 or more times/wk | 4 (3.2) | 16 (5.2) | 0.60 (0.14-1.92) | |
| Consumption of grilled/barbecued meat | ||||
| 0-2 times/mo | 69 (55.2) | 217 (70.7) | Ref. | 0.0211 |
| 3 or more times/mo | 56 (44.8) | 90 (29.3) | 1.72 (1.08-2.75) | |
| Alcohol drinking | ||||
| 0-3 times/wk | 110 (88) | 268 (86.5) | Ref. | 0.665 |
| 4 or more times/wk | 15 (12) | 42 (13.5) | 0.87 (0.43-1.68) | |
| Consumption of coffee | ||||
| < 1 cup/d | 90 (72) | 259 (83.5) | Ref. | 0.0371 |
| 1 or more cups/d | 35 (28) | 51 (16.5) | 1.77 (1.03-3.03) | |
| GSTT1 | ||||
| Presence | 100 (82) | 245 (81.7) | Ref. | 0.942 |
| Null | 22 (18) | 55 (18.3) | 0.98 (0.54-1.74) | |
| GSTM1 | ||||
| Presence | 61 (50) | 160 (53.3) | Ref. | 0.534 |
| Null | 61 (50) | 140 (46.7) | 1.14 (0.73-1.78) | |
| CYP1A1 | ||||
| TT | 64 (52.5) | 140 (46.7) | Ref. | 0.280 |
| TC + CC | 58 (47.5) | 160 (53.3) | 0.79 (0.51-1.24) |
- Citation: Cerliani MB, Pavicic W, Gili JA, Klein G, Saba S, Richard S. Cigarette smoking, dietary habits and genetic polymorphisms in GSTT1, GSTM1 and CYP1A1 metabolic genes: A case-control study in oncohematological diseases. World J Clin Oncol 2016; 7(5): 395-405
- URL: https://www.wjgnet.com/2218-4333/full/v7/i5/395.htm
- DOI: https://dx.doi.org/10.5306/wjco.v7.i5.395