Cigarette smoking, dietary habits and genetic polymorphisms in GSTT1, GSTM1 and CYP1A1 metabolic genes: A case-control study in oncohematological diseases

Table 1 Demographic characteristics of the population under study n (%)

	Cases n = 125	Controls n = 310	OR (95%CI)	P
Age mean (SD)	48.5 (16.6)	51 (18.5)	-	0.507
Sex
Male	74 (59.2)	134 (43.2)	Ref.	0.003
Female	51 (40.8)	176 (56.8)	0.52 (0.34-0.82)
Education
≤ 7 yr (complete primary school or less)	174 (56.31)	55 (44)	Ref.
12 yr (complete secondary school)	115 (37.22)	48 (38.4)	1.2 (0.73-1.95)	< 0.0011
> 12 yr (complete college)	20 (6.47)	22 (17.6)	3.68 (1.82-7.4)
Marital status
Single	79 (25.48)	27 (21.6)	Ref.
In couple/married	162 (52.26)	86 (68.8)	1.7 (0.99-2.95)	0.051
Divorced/separated	27 (8.71)	5 (4)	0.64 (0.21-1.9)	0.421
Widowed	42 (13.55)	7 (5.6)	0.75 (0.27-2.13)	0.591
Type of malignancy
ALL	10 (8)
AML	18 (14.4)
CLL	10 (8)
CML	20 (16)
MM	29 (23.2)
HL	18 (14.4)
NHL	20 (16)

¹Adjusted for age and sex. P < 0.05 considered statistically significant. ALL: Acute lymphoblastic leukemia; AML: Acute myeloblastic leukemia; CLL: Chronic lymphoblastic leukemia; CML: Chronic myeloblastic leukemia; MM: Multiple mieloma; HL: Hodgkin lymphoma; NHL: Non-Hodgkin lymphoma; Ref: Reference category; SD: Standard deviation.