Retrospective Cohort Study
Copyright ©The Author(s) 2016.
World J Clin Oncol. Jun 10, 2016; 7(3): 302-307
Published online Jun 10, 2016. doi: 10.5306/wjco.v7.i3.302
Table 1 Patient characteristics
UM
CPM
P value
n = 759 (94%)n = 52 (6%)
Age (median years, range)52 (28-88)49 (29-67)< 0.001
Pre-operative diagnosis (%)0.74
Invasive carcinoma only585 (77.1)38 (73.1)
DCIS only144 (19.0)12 (23.1)
Invasive + DCIS30 (4.0)2 (3.8)
Previous benign disease (%)0.26
No566 (74.6)34 (65.4)
Yes164 (21.6)15 (28.8)
Unknown29 (3.8)3 (5.8)
Pre-op BRCA1/BRCA2 mutation status (%)< 0.001
Negative43 (6)9 (17)
Positive6 (1)11 (21)
Both unknown710 (94)32 (62)
Family history (%)< 0.001
Positive283 (37.3)35 (67.3)
Negative440 (58.0)13 (25.0)
Unknown36 (4.7)4 (7.7)
Pre-op systemic therapy (%)0.23
No588 (77)36 (69)
Yes171 (23)16 (31)
Any radiation treatment (%)0.008
No435 (57)40 (77)
Yes324 (43)12 (23)
SLNB (%)0.76
No316 (42)20 (38)
Yes443 (58)32 (62)
ALND (%)< 0.001
No387 (51)10 (19)
Yes372 (49)42 (81)
Reconstruction (%)< 0.001
No695 (92)24 (46)
Yes64 (8)28 (54)
Local/regional recurrence (%)0.68
No734 (97)50 (96)
Yes25 (3)2 (4)
New contralateral breast cancer (%)0.05
No746 (98)49 (94)
Yes13 (2)3 (6)
Follow-up (median years, range)2.32 (0.04-7.15)2.54 (0.13-6.91)0.56