Overview, prevention and management of chemotherapy extravasation

Table 5 Pharmacological management of chemotherapy extravasation

Dexrazoxane as an antidote to anthracyclines extravasation has level III-B evidence[16]

Hyaluronidaseas an antidote to vinca-alkaloids and to taxanes extravasation has level V-C evidence[16]

Topical DMSO (99%) as an antidote to anthracycline extravasation and to Mytomicin C has level IV-B evidence[16]

Sodium thiosulfate as an antidote to mechlorethamine extravasation has level V-C evidence[16]

DMSO: Dimethyl sulfoxide.