Fluoxetine induces cytotoxic endoplasmic reticulum stress and autophagy in triple negative breast cancer

Figure 2 Time-dependent and concentration-dependent inhibition of cell growth induced by fluoxetine. A: Bright field images of late and early passage of MCF10A cells were shown in 20 × magnification; B-F: The IC₅₀ values for the dose-response curves for each cell line were also indicated; cell viability for each cell line was measured spectrophotometrically by means of MTT assay. Data represented the average of optical densities normalized to untreated samples ± SEM of 6 measurements for each concentration. MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; FLX: Fluoxetine.