Portal vein embolization effect on colorectal cancer liver metastasis progression: Lessons learned

Table 1 Summary of several studies describing the effect of portal vein embolization on tumor progression

Ref.	No. of CRLM patients undergoing PVE	Percentage change in tumor volume and/or TGR and/or percentage of patients developing tumor progression after PVE
Simoneau et al[13]	n = 109	33.4% increase in TV in the right lobe (P < 0.001) and 49.9% increase in TV in the left lobe (P = 0.022) post-PVE
Elias et al[14]	n = 48	60% to 970% increase in TV post-PVE
Kokudo et al[15]	n = 18	+20.8% (P = 0.016) increase in TV and 18.5% (P = 0.014) increase in percent tumor volume post-PVE
Mueller et al[19]	n = 53	80.9% (n = 17/53) of patients were unresectable due to tumor progression post-PVE
Pamecha et al[21]	n = 36	33% (n = 12/36) of patients had tumor progression post-PVE
Hoekstra et al[22]	n = 28	25% (n = 7/28) of patients developed new lesions in FLR and 42% of patients (n = 8/19) had tumor recurrence in the liver on follow up post-PVE
Pamecha et al[23]	n = 22	TGR post-PVE was 0.36 ± 0.68 mL/d (-1) (P = 0.06)
Lindner et al[24]	n = 19	21% of patients developed tumor progression post-PVE

CRLM: Colorectal liver metastasis; PVE: Portal vein embolization; TV: Tumor volume; TGR: Tumor growth rate.