Axillary lymph node management in breast cancer with positive sentinel lymph node biopsy

Table 1 Trials discussed in this paper informing directly or indirectly on the question of completion of axillary lymph node dissection in patients with sentinel lymph node biopsy-positive breast cancer patients

Trial [Ref.]	Comment
ACOSOG Z0011[7]	The main randomized trial informing the clinical question
IBCSG 23-01[8]	Randomized trial in patients with micrometastatic only axillary disease
Yegiyants et al[14]	Small study of patients followed after micrometastases found in SLN biopsy
Martelli et al[15]	Randomized trial comparing ALND vs no surgery in older patients
IBCSG Trial 10-93[16]	Similar to reference 15
Avril et al[17]	Similar to references 15 and 16 but in a younger patient population
Louis-Sylvestre et al[19]	Randomized trial comparing ALND with axillary radiation treatment
Wang et al[21]	Retrospective SEER-based study in patients with lobular carcinomas

SLN: Sentinel lymph node; ALND: Axillary lymph node dissection; SEER: Surveillance, Epidemiology and End Results.