MiR-210 expression reverses radioresistance of stem-like cells of oesophageal squamous cell carcinoma

Figure 4 Double-strand break-related changes in protein expression in miR-210 up-regulated radioresistant oesophageal squamous cell carcinoma cells. A: The expression levels of ataxia telangiectasia mutated (ATM) and DNA dependent protein kinase (DNA-PKcs) in transfected and control TE-1R cells. The mRNA levels were determined using reverse transcription-polymerase chain reaction. The protein levels were determined using Western blot. The experiments were performed in triplicate. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was used as the internal reference; B: Histogram showing the levels of ATM and DNA-PKcs protein expression in transfected and control TE-1R cells. ^aP < 0.05, pmiR-210 vs Ctrl.