Chemotherapy advances in locally advanced head and neck cancer

doi:10.5306/wjco.v5.i5.966

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Dec 10, 2014 (publication date) through Jul 21, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Dec 10, 2014; 5(5): 966-972
Published online Dec 10, 2014. doi: 10.5306/wjco.v5.i5.966

Table 2 DeCIDE and PARADIGM results

Study	Patients	Randomization (induction regimens)	PFS (3 yr)	OS (3 yr)	DM
PARADIGM	145	CRT	69%	78%	11%
PARADIGM	145	TPF (3) → CRT	67%	73%	7%
DeCIDE	280	CRT	59%	73%	19%¹
DeCIDE	280	TPF (2) → CRT	67%	75%	10%¹

¹Statistically significant. CRT: Chemoradiation; DM: Distant metastasis.

Citation: Georges P, Rajagopalan K, Leon C, Singh P, Ahmad N, Nader K, Kubicek GJ. Chemotherapy advances in locally advanced head and neck cancer. World J Clin Oncol 2014; 5(5): 966-972
URL: https://www.wjgnet.com/2218-4333/full/v5/i5/966.htm
DOI: https://dx.doi.org/10.5306/wjco.v5.i5.966