Palliative radiotherapy for bone metastases from lung cancer: Evidence-based medicine?

Table 2 Evidence supporting recommended dose-fractionation schedules

Indication	Recommended schedule	Selected references	Level of evidence
Uncomplicated bone metastases (spine, non-spine)		[15]	1
	8Gy/1	[10,32,39,41,60,61]	5
Neuropathic pain	8Gy/1 or 20Gy/5	[38]	1
Impending SCC, RT alone	Multifraction	[41]	5
		[36]	4
Impending pathologic fracture, RT alone	20-40Gy/5-20	[45]	1

RT: Radiotherapy; SCC: Spinal cord compression.