Risk factors and natural history of breast cancer in younger Chinese women

doi:10.5306/wjco.v5.i5.1097

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Dec 10, 2014 (publication date) through Jul 27, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Dec 10, 2014; 5(5): 1097-1106
Published online Dec 10, 2014. doi: 10.5306/wjco.v5.i5.1097

Table 4 Treatments received by patients with invasive breast tumours (n = 5523)

	< 40 yr (n = 706) n (%)	≥40 yr (n = 4817) n (%)	P value
Surgery
Breast conserving surgery	324 (46.1)	1638 (34.3)	χ² = 36.921, ^bP < 0.001
Mastectomy	379 (53.9)	3135 (65.7)	χ² = 36.921, ^bP < 0.001
Reconstruction
Yes	135 (35.7)	367 (11.7)	χ² = 158.189, ^bP < 0.001
No	243 (64.3)	2762 (88.3)	χ² = 158.189, ^bP < 0.001
Nodal Surgery
Sentinel node biopsy (SNB)	222 (32.2)	1351 (28.7)	χ² = 8.496, ^aP = 0.014
Axillary dissection (AD)	336 (48.7)	2572 (54.6)
SNB+AD	132 (19.1)	787 (16.7)
Chemotherapy
Stage I	151 (59.2)	633 (39.7)	χ² = 34.433, ^bP < 0.001
Stage IIA	210 (88.6)	1291 (83.8)	χ² = 3.572, P = 0.067
Stage IIB	97 (100)	631 (91.1)	χ² = 9.417, ^bP < 0.001
Stage III	72 (98.6)	664 (93.7)	NA¹
Stage IV	8 (100)	69(89.6)	NA¹
Radiotherapy (overall)
All patients	496 (72)	3106 (66.2)	χ² = 9.189, ^bP = 0.002
BCS patients	306 (96.2)	1522 (95.4)	χ² = 0.460, P = 0.556
MTX patients	190 (51.6)	1564 (51.2)	χ² = 0.027, P = 0.912
Irradiated regions (overall)
Breast ± regional lymph nodes	187 (60.1)	998 (46)	χ² = 21.859, ^bP < 0.001
Chest wall ± regional lymph nodes	124 (39.9)	1173 (54)	χ² = 21.859, ^bP < 0.001
Endocrine therapy	477 (68.7)	3496 (74.2)	χ² = 9.206, ^bP = 0.003
Targeted therapy	59 (8.6)	339 (7.2)	χ² = 1.682, P = 0.211

¹χ²-test was not available due to the small number of patients.

Citation: Yeo W, Lee HM, Chan A, Chan EY, Chan MC, Chan KW, Chan SW, Cheung FY, Cheung PS, Choi PH, Chor JS, Foo WW, Kwan WH, Law SC, Li LP, Tsang JW, Tung Y, Wong LL, Wong TT, Yau CC, Yau TK, Zee BC. Risk factors and natural history of breast cancer in younger Chinese women. World J Clin Oncol 2014; 5(5): 1097-1106
URL: https://www.wjgnet.com/2218-4333/full/v5/i5/1097.htm
DOI: https://dx.doi.org/10.5306/wjco.v5.i5.1097