MiR-210 expression reverses radioresistance of stem-like cells of oesophageal squamous cell carcinoma

Table 3 Radiobiological indices of the pmiR-210 and Ctrl cells

	D0	Dq	N	SF2
PmiR-210	1.73% ± 0.01%	1.56% ± 0.02%a	1.97% ± 0.03%a	43.62% ± 0.14%a
Ctrl	1.75% ± 0.02%	1.89% ± 0.13%	3.13% ± 0.07%	67.83% ± 0.16%

^aP < 0.05, vs Ctrl. PmiR-210: TE-1R cells transfected with the miR-210 mimic; Ctrl: TE-1R cells transfected with a nonsense sequence. The experiments were performed in triplicate. D₀: Mean lethal dose; D_q: Quasi-threshold dose; N: Extrapolated number; SF₂: Survival fraction after 2-Gy irradiation. The lower D_q and N of the pmiR-210 cells compared with those of the Ctrl cells indicate a less efficient repair of radiation damage. A low SF₂ value indicates a level of high sensitivity to radiotherapy.