Effects of psoralens as anti-tumoral agents in breast cancer cells

doi:10.5306/wjco.v5.i3.348

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Aug 10, 2014 (publication date) through Jul 23, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Aug 10, 2014; 5(3): 348-358
Published online Aug 10, 2014. doi: 10.5306/wjco.v5.i3.348

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Figure 1 Interaction between psoralen and DNA. Upon absorption of ultraviolet radiation A (UVA) photons, the psoralen excited state can react with a thymine and covalently attach the DNA. The initial photoadduct can absorb a second UVA photon and react with a second thymine on the opposing strand of DNA helix to crosslink the two strands.

Citation: Panno ML, Giordano F. Effects of psoralens as anti-tumoral agents in breast cancer cells. World J Clin Oncol 2014; 5(3): 348-358
URL: https://www.wjgnet.com/2218-4333/full/v5/i3/348.htm
DOI: https://dx.doi.org/10.5306/wjco.v5.i3.348