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World J Clin Oncol. Aug 10, 2014; 5(3): 348-358
Published online Aug 10, 2014. doi: 10.5306/wjco.v5.i3.348
Published online Aug 10, 2014. doi: 10.5306/wjco.v5.i3.348
Figure 1 Interaction between psoralen and DNA.
Upon absorption of ultraviolet radiation A (UVA) photons, the psoralen excited state can react with a thymine and covalently attach the DNA. The initial photoadduct can absorb a second UVA photon and react with a second thymine on the opposing strand of DNA helix to crosslink the two strands.
- Citation: Panno ML, Giordano F. Effects of psoralens as anti-tumoral agents in breast cancer cells. World J Clin Oncol 2014; 5(3): 348-358
- URL: https://www.wjgnet.com/2218-4333/full/v5/i3/348.htm
- DOI: https://dx.doi.org/10.5306/wjco.v5.i3.348