Pleomorphic lobular carcinoma in situ of the breast: Can the evidence guide practice?

Table 2 Rate of recurrent disease after surgical excision of pleomorphic lobular carcinoma in situ

Ref.	No. of PLCIS cases	PLCIS at margin	Histology of recurrence	Time to recurrence	Local recurrence rate
Downs-Kelly et al[5]	26	13 cases ≤ 1 mm 4 cases 1.1-2 mm 9 cases > 2 mm	1 PLCIS	19 mo	3.8%
Khoury et al[35]	57	Not stated	7 PLCIS	Not stated	12.3%
Fasola et al[30]	34	Not stated	3 PLCIS	≤ 5 yr	8.85

This details the number of cases of histologically diagnosed recurrence following a previous excision of PLCIS. PLCIS: Pleomorphic lobular carcinoma in situ.