Monitoring adenoviral based gene delivery in rat glioma by molecular imaging

Figure 3 Histological analysis of intratumor injection and migration of cells. Animal brain sections were stained with Prussian blue and observed under light microscope. Center image (magnification × 2) shows the iron positive cells at injection site and migration around periphery and inside the tumor. Images × 2 shows the whole tumor area and injection sites and images × 40 shows iron labeled cell at injection site and around the tumor. Images × 40 were linked to images × 2 with arrow to show the region × is 40 near to the arrows (not exact match). These images indicate the migration of transgenic endothelial progenitor cells (EPCs) to periphery of the tumor from the injection site. Some of the EPCs were also migrated to the center of the tumor from the injection site. IS: Injection site.