Combined chemo-radiotherapy in locally advanced nasopharyngeal carcinomas

Table 1 Patients characteristics

Characteristic	Patients
Total	40
Male	33
Female	7
Age, yr, median (range)	60 (24-82)
Stage
IIb	3
III	18
IVa	15
IVb	4
ECOG performance status
0	36
1	4
2	0
Treatment performed induction CT followed by
CCRT1	22
CCRT2	18
Total	40
Induction chemotherapy scheme
PF3	9
TPF4	3
TP5	9
BMC6	1
Total	22
Total radiation dose delivered
70 Gy	36
68 Gy	3
66 Gy	1
Histology squamous cell
G1	1
G2	2
G3	4
Undifferentiated	33

¹Induction chemotherapy followed by concomitant chemo-radiotherapy;

²Concurrent chemoradiotherapy;

³Cisplatin (100 mg/m² every 3 wk) and 5-fluorouracil (5-FU) (1000 mg/m² per day, 4-d continuous infusion every 3 wk);

⁴Docetaxel (75 mg/m² every 3 wk), cisplatin (75 mg/m² every 3 wk) and 5-FU (750 mg/m² per day, 4-d continuous infusion every 3 wk);

⁵Docetaxel (75 mg/m² every 3 wk) and cisplatin (75 mg/m² every 3 wk);

⁶Bleomycin (25 mg/m² on days 1 and 8 of a 21-d cycle), methotrexate (35 mg/m² weekly) and cisplatin (80 mg/m² every 3 wk). ECOG: Eastern Cooperative Oncology Group; CT: Computed tomography.