Analysis of the Hox epigenetic code

Table 4 Ubiquitin-conjugating enzymes in Caenorhabditis elegans: homologs and loss-of-function phenotypes

C. elegans	Peptide-conjugated	Human	Phenotypes
ubc-1	Ub	UBE2A; UBE2B	WT (RNAi)
ubc-2/let-70	Ub	UBE2D1/UBCH5A; UBE2D2/UBCH5B; UBE2D3/UBCH5C	embryonic arrest at pre-comma stage (RNAi)
ubc-3	Ub	CDC34; FLJ20419	WT (RNAi)
ubc-6	Ub	NCUBE1	WT (RNAi)
ubc-7	Ub	UBE2G1	WT (RNAi)
ubc-8	Ub	UBE2H	WT (RNAi)
ubc-9	SUMO	UBE2I	embryonic arrest post- gastrulation before muscle movement (RNAi)
ubc-12	NED-8 (Nedd8)	UBE2M	embryonic arrest at the comma stage (RNAi)
ubc-13	Ub	UBE2N; BAA93711	WT (RNAi)
ubc-14	Ub	UBE2G2	embryonic arrest post- gastrulation before muscle movement (RNAi)
ubc-15	Ub	NCUBE1	WT (RNAi)
ubc-18	Ub	UBE2L1; UBE2L3/ UBCH7; UBE2L6	reduced growth rate and brood size (mut)
ubc-20	Ub	HIP2	impenetrant L3 and L4 larval arrest (RNAi)
ubc-21	Ub	HIP2	WT (RNAi)
ubc-22	Ub	UBE2L1; UBE2L3/ UBCH7; UBE2L6	WT (RNAi)
ubc-23	Ub	HIP2	WT (RNAi)