Rituximab maintenance in follicular lymphoma patients

Table 2 Randomized trials comparing rituximab maintenance vs observation after single agent rituximab

Reference	Year	Prior treatment	Maintenance schedule	No. of patients	Median F-up	PFS	OS
Haisworth et al[16]	2005	R x 4 (weekly)	R x 4 (weekly) every 6 mo x 4 vs R x 4 weekly at relapse (retreatment)	62	41 mo	31.3 vs 7.4 mo (P = 0.007)	72% vs 68% at 3 years (P = NS)
Ghielmini et al[14] Martinelli et al[19]	2004	R x 4 (weekly)	R every 2 mo x 4 vs observation	185	9.5 years	24 vs 13 mo (P < 0.001)	68% vs 54% (P = 0.081)
	2010