High intensity focused ultrasound in clinical tumor ablation

Table 1 Summary of most popular high-intensity focused ultrasound system for clinical use

Model	Manufacturer	Size (mm)	Focal length (mm)	Frequency (MHz)	Focusing method	Imaging guidance	Clinical applications
FEP-BY02	Beijing Yuande Biomedical Engineering Inc, China	OD = 370 ID = 120	255	1	251 elements driven in phase	GE Logiq series ultrasound system	Liver, kidney, breast, pancreatic, bone tumor and uterine fibroid
Model-JC	Chongqing Haifu Tech Ltd, China	D = 120 or 150	90, 130, 160	0.8, 1.6, 3.2	Flat ceramics with acoustic lens	AU3 ultrasound imaging system	Liver, kidney, breast, pancreatic, bone tumor and uterine fibroid
ExAblate 2000	InSightec Ltd, Israel	120	150	0.9, 1.3	Phased array 208 hexagonal elements, 3 cavitation detector	GE Signa 1.5/3.0T MR imaging system	Uterine fibroids, breast tumor, liver cancer, bone metastases, neurosurgery, prostate cancer
Sonalleve	Philips, USA	N/A	N/A	1.2, 1.4	Phased array	Philips Achieva 1.5/3.0T MR imaging system	Uterine fibroids
Sonablate 500	Focus Surgery Inc., USA	30 × 22	30 and 40 or 45/50	4	2 elements mounted back-to-back	Element for both therapy and imaging	Prostate cancer
Ablatherm	Edap-Technomed, France	40 × 22 ID = 8	45	3	Single concave element	7.5 MHz integrated ultrasound imaging	Prostate cancer
TH-One	Theraclion, France	56	38	3	Single concave element	B-K Medical ultrasound imaging system	Hyperparathyroidism

N/A: Not available; GE: General electronics; MR: Magnetic resonance.