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Copyright ©The Author(s) 2025.
World J Clin Oncol. Apr 24, 2025; 16(4): 104785
Published online Apr 24, 2025. doi: 10.5306/wjco.v16.i4.104785
Table 4 Comparative studies on comprehensive geriatric assessment vs standard care in oncology nursing
Study
Country/region
Key findings
Cancer types studied
Outcomes measured
French OGS toolFranceDeveloped and validated a short decision-making algorithm-OGS with high sensitivity to identify frail patients requiring CGA, optimizing treatment decisionsVarious cancersIdentification of frail patients, treatment decision-making[18]
CGA in older cancer patientsUnited StatesMeta-analysis of 28 trials (4959 subjects) showed CGA effectively identifies patients benefiting from geriatric evaluation, reducing morbidity and improving physical and cognitive functionVarious cancersMorbidity reduction, physical and cognitive function improvement[23,59]
CGA in cancer careAustraliaIntegrating CGA into oncology care improved treatment completion rates, reduced grade 3+ chemotherapy toxicity, and enhanced quality of life scoresVarious cancersTreatment completion rates, chemotherapy toxicity, quality of life scores[27]
Geriatrician-delivered CGA impactUnited KingdomDemonstrated that geriatrician-led CGA is associated with better outcomes for older patients undergoing chemotherapy compared to standard careVarious cancersTreatment tolerance, overall survival[63]
CGA predicting overall survivalSingaporeCGA predicted overall survival in patients aged ≥ 70 with solid tumors, aiding in personalized treatment plansSolid tumorsOverall survival prediction[23]
CGA in primary careNetherlandsCGA adapted for primary care did not reduce emergency visits but provided insights into patient needs, suggesting areas for care improvementVarious cancersEmergency department visits, care planning[64]