Candida albicans and colorectal cancer: A paradoxical role revealed through metabolite profiling and prognostic modeling

Figure 4 Kaplan-Meier survival curves. The Kaplan-Meier survival curves are presented with the horizontal axis representing survival time (t) and the vertical axis indicating the probability of an individual surviving beyond time t. High expression groups are shown in red, while low expression groups are depicted in blue. Differences between survival curves were evaluated using a log-rank test with a significance threshold of P < 0.05. X represents different EHD4, FDFT1, GADD45B, LIME1, TIMP1 expression levels of the patients. The Y-axis represents proportions, with the total ratio of dead to alive patients in groups with different expression levels being 1, with red representing patients who died and blue representing patients who were alive. A: FDFT1; B: TIMP1; C: GADD45B; D: LIME1; E: EHD4. From left to right are overall survival (OS), disease-specific survival (DSS), progression-free interval, and disease-free interval; F: EHD4, LIME1, GADD45B survival_ OS-status; G1: GSE17537 _GADD45B_Survival_ Chi-Square_test_RFS; G2: GSE17537_ GADD45B_ Survival _Chi-Square_test_OS; H1: GSE17536 _ GADD45B _ Survival_Chi-Square _test _RFS; H2: GSE17536_GADD45B_ Survival_ Chi-Square_ test_ OS; I: TIMP1. CRC. Survival. Chi-Square. Test; J1: GSE87211_ TIMP1_ Survival_ Chi -Square_test_RFS; J2: GSE87211_ TIMP1_Survival_Chi-Square _test_DSS; J3: GSE29621 _TIMP1 _ Survival_ Chi-Square _test_RFS; K1: GSE17536_ TIMP1_ Survival_ Chi-Square _test_RFS; K2: GSE17536_ TIMP1_ Survival_ Chi-Square _test_DSS; L: TIMP1, survival of FDFT1, _OS-Status; M1: GSE72970_FDFT1 _Survival_ Chi-Square_test_PFS; M2: GSE72970 _FDFT1_Survival_Chi-Square_test_OS; N: GSE12945_ FDFT1_ Survival _Chi-Square_test_OS. CRC: Colorectal cancer.