Candida albicans and colorectal cancer: A paradoxical role revealed through metabolite profiling and prognostic modeling

Figure 1 Establishment of prognostic model and enrichment analysis. A: Volcano plot depicting differential gene expression; B: Forest plot highlighting notable mRNAs; C and D: Least absolute shrinkage and selection operator model selection and feature identification; E: Distribution of risk scores and heatmap of mRNA expression in The Cancer Genome Atlas colorectal cancer dataset. E1: Overall risk score distribution. E2: Training set. E3: Test set. E4: Gene Expression Omnibus (GEO) datasets; F: Kaplan-Meier survival analysis. F1: Total risk score. F2: Training set. F3: Test set. F4: GEO datasets; G: Time-dependent receiver operating characteristic curves. G1: Entire dataset. G2-G4: Training set, test set, and GEO datasets, respectively; H: Volcano plot of differential genes; I: Enrichment results. I1: Biological processes. I2: Molecular function. I3: Cellular component. I4: Kyoto Encyclopedia of Genes and Genomes pathways. HR: Hazard ratio; AUC: Area under the curve.