Downregulation of huntingtin-associated protein 1 predicts poor prognosis in gastric cancer

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Apr 24, 2025 (publication date) through Apr 1, 2025

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Apr 24, 2025; 16(4): 102958
Published online Apr 24, 2025. doi: 10.5306/wjco.v16.i4.102958

Table 1 Expression of huntingtin-associated protein 1 in patients with gastric cancer

Groups	HAP1 expression				Total
Groups	-	+	++	+++	Total
Adjacent normal mucosas	11	27	33	53	124
GC tissues	48	37	28	11	124¹
GC tissues with lymphatic metastasis	30	28	10	8	76²
GC tissues without lymphatic metastasis	17	10	11	10	48
Lymphatic metastasis tissues	45	12	13	6	76³

¹Adjacent normal mucosas vs gastric cancer tissues; χ² = 35.631, P < 0.001.

²Gastric cancer tissues with lymphatic metastasis vs gastric cancer tissues without lymphatic metastasis; χ² = 5.494, P = 0.019.

³Adjacent normal mucosas vs lymphatic metastasis tissues; χ² = 39.376, P < 0.001.

HAP1: Huntingtin-associated protein 1; GC: Gastric cancer.

Citation: Wang XY, Yang FH, Yuan ZY, Wang ZJ, Zhang HF, Xu ZH. Downregulation of huntingtin-associated protein 1 predicts poor prognosis in gastric cancer. World J Clin Oncol 2025; 16(4): 102958
URL: https://www.wjgnet.com/2218-4333/full/v16/i4/102958.htm
DOI: https://dx.doi.org/10.5306/wjco.v16.i4.102958