Construction of a nomogram-based risk prediction model for depressive symptoms in middle-aged and young breast cancer patients

Table 1 Baseline characteristics of patients with and without depression, n (%)

Characteristic	Non-depressed group (n = 221)	Depression group (n = 139)	P value
Age (mean ± SD), years	47.34 ± 8.914	51.66 ± 6.159	< 0.001b
BMI (mean ± SD)	23.68 ± 3.19	24.60 ± 3.44	0.011a
Marital status			0.431
Married	211 (95.48)	135 (97.12)
Unmarried/divorced/widowed	10 (4.52)	4 (2.88)
Type of health insurance			0.052
Urban employee health insurance	155 (70.14)	81 (58.27)
Urban and rural resident health insurance	47 (21.27)	45 (32.37)
Uninsured	19 (8.60)	13 (9.35)
Place of residence			< 0.001b
Rural	43 (19.46)	54 (38.85)
Urban	178 (80.54)	85 (61.15)
Surgical approach			0.286
No surgery	59 (26.70)	29 (20.86)
Total mastectomy	109 (49.32)	80 (57.55)
Breast conserving surgery	53 (23.98)	30 (21.58)
Smoking history			0.574
Yes	3 (1.36)	1 (0.72)
No	218 (98.64)	138 (99.28)
Drinking history			0.562
Yes	1 (0.45)	2 (1.44)
No	220 (99.55)	137 (98.56)
Family history of tumors			0.602
Yes	10 (4.52)	8 (5.76)
No	211 (95.48)	131 (94.24)
Lymph node metastasis			0.181
Yes	139 (62.90)	97 (69.78)
No	82 (37.10)	42 (30.22)
Treatment method			0.269
Chemotherapy	144 (65.16)	82 (58.99)
Chemotherapy/targeted therapy	64 (28.96)	43 (30.94)
Radiotherapy/endocrine therapy/other	13 (5.88)	14 (10.07)
Education level			< 0.001b
High school or above	131 (59.28)	23 (16.55)
Junior high school or below	90 (40.72)	116 (83.45)
Menopausal status			< 0.001b
Yes	136 (61.54)	118 (84.89)
No	85 (38.46)	21 (15.11)
Adverse reactions			< 0.001b
Yes	84 (38.01)	127 (91.37)
No	137 (61.99)	12 (8.63)
Duration of illness [M (P25, P75)]	18.52 (3.00, 7.00)	24.81 (3.00, 24.00)	0.033a
Tumor grade			< 0.001b
I	150 (67.87)	12 (8.63)
II	58 (26.24)	66 (47.48)
III	13 (5.88)	61 (43.88)
Distant metastasis			< 0.001b
Yes	40 (18.10)	53 (38.13)
No	181 (81.90)	86 (61.87)
Patient's monthly income, RMB yuan			< 0.001b
< 3000	39 (17.65)	128 (92.09)
≥ 3000 but < 5000	82 (37.10)	8 (5.76)
≥ 5000	100 (45.25)	3 (2.16)
Pain score [M (P25, P75)]	0.06 (0.00, 0.00)	3.86 (2.00, 5.00)	< 0.001b
Level of physical activities			< 0.001b
Active	131 (59.28)	7 (5.04)
Suitable	83 (37.56)	11 (7.91)
Insufficient	7 (3.17)	121 (87.05)
Family support level			< 0.001b
Low level	5 (2.26)	35 (25.18)
Medium level	10 (4.52)	100 (71.94)
High level	206 (93.21)	4 (2.88)

^aP < 0.05.

^bP < 0.001.

BMI: Body mass index.