Transmembrane channel-like 5 drives hepatocellular carcinoma progression by regulating epithelial-mesenchymal transition

Figure 1 Bioinformatics and prognosis analyses of transmembrane channel-like 5 expression. A and B: The expression profile of transmembrane channel-like 5 (TMC5) in different cancers and normal tissues was determined using GENT2; C: Pan-cancer analysis of TMC5 mRNA expression using the GEPIA database; D: Expression of TMC5 between hepatocellular carcinoma (HCC) and paired normal liver tissues based on the GEPIA database; E: Immunohistochemistry showing TMC5 expression in normal liver tissues from The Human Protein Atlas database; F: Overall survival curve of TMC5 in HCC patients in GEPIA dataset; G: Construction and validation of the nomogram based on TMC5 expression and clinical characteristics (gender, age, stage, T stage, N stage, and M stage); H: Calibration analysis based on the nomogram. ^aP < 0.05; ^bP < 0.01. TMC5: Transmembrane channel-like 5.