Targeting STAT3 with SH-4-54 suppresses stemness and chemoresistance in cancer stem-like cells derived from colorectal cancer

Figure 6 SH-4-54 inhibited tumor growth of cancer stem cells in vivo. A: 5 × 10⁵ cancer stem cells derived from SW480 was planted subcutaneously in nude mice and maintained for 30 days. Tumor growth curve (left panel) and animal weight curve (right panel) was drawn; B and C: Tumor tissues were fixed and sectioned for H&E staining (B) and Ki67 staining (C). ^aP < 0.05 vs mock group.