Preparation of kakkatin derivatives and their anti-tumor activity

Figure 5 Network pharmacological effects of 6-(hept-6-yn-1-yloxy)-3-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one and hepatocellular carcinoma SMMC-7721 cells. A: Cross-Venn diagram of 6-(hept-6-yn-1-yloxy)-3-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one (HK)-related targets and SMMC-7721 cells; B: Gene Ontology enrichment analysis of 49 potential targets of HK in the treatment of SMMC-7721 cells; C: Kyoto Encyclopedia of Genes and Genomes enrichment analysis of 49 potential targets of HK in the treatment of SMMC-7721 cells; D: Correlation network analysis of 49 potential targets of HK in the treatment of SMMC-7721 cells; E: Correlation of 49 targets with HK. GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes.