Hsa-miR-483-5p/mRNA network that regulates chemotherapy resistance in locally advanced rectal cancer identified through plasma exosome transcriptomics

Figure 4 The survival analysis of target genes of hsa-miR-483-5p using TCGA database. A: The up-regulation of hsa-miR-483-5p is associated with a relatively poor survival outcomes in breast cancer patients, suggesting its role in the pathogenesis of tumors; B and C: Demonstrated that the low-expression of target genes of RAX2 and RNF165 are correlated with better 5 years-overall survival in colorectal cancer patients; D-F: Represents that the low-expression of target genes of RAX2, RNF165, and MAPK3 are positively associated with superior 5 years-recurrence-free survival, correspondingly. OS: Overall survival; RFS: Recurrence-free survival; CRC: Colorectal cancer; HR: Hazard ratio.