Biomarkers associated with immune-related adverse events induced by immune checkpoint inhibitors

Figure 3 Methods that enable the discovery of new biomarkers. This includes multiomics analysis, single-cell RNA sequencing, machine learning, and gut microflora analysis. A: Integrated analysis of mutiomics; B: Single-cell RNA sequencing; C: Machine learning; D: Gut microbiota. scRNA-seq: Single-cell RNA sequencing; irAEs: Immune-related adverse events; ICI: Immune checkpoint inhibitors; APC: Antigen-presenting cells.