Retrospective Study
Copyright ©The Author(s) 2024.
World J Clin Oncol. Aug 24, 2024; 15(8): 1033-1047
Published online Aug 24, 2024. doi: 10.5306/wjco.v15.i8.1033
Table 3 Univariate and multivariate cox regression analysis for overall survival
VariablesOS
HR (95%CI)
P value
Univariate analysis
Gender (male vs female)0.922 (0.729-1.165)0.496
Age (< 65 vs ≥ 65)1.315 (1.080-1.604)0.007
Clinical stage
I1 (Reference)
II2.876 (1.735-4.768)0.000
III8.712 (5.601-13.552)0.000
T stage
T11 (Reference)
T21.693 (0.889-3.227)0.019
T34.438 (2.634-7.478)0.000
T46.330 (3.981-10.065)0.000
N stage
N01 (Reference)
N12.330 (1.667-3.257)0.000
N23.239 (2.383-4.401)0.000
N35.201 (3.957-6.836)0.000
Location
Cardia1 (Reference)
Gastric body1.306 (1.025-1.664)0.031
Antrum of stomach1.698 (1.276-2.261)0.000
Pathological type (adenocarcinoma vs other)1.209 (0.807-1.813)0.358
Differentiation (well, high and medium vs moderate to low and poor)1.776 (1.392-2.265)0.000
Borrmann type (III vs other)0.579 (0.462-0.724)0.000
Size (< 5 vs ≥ 5)0.403 (0.329-0.494)0.000
AFP (positive vs negative)1.929 (1.520-2.448)0.000
CEA (positive vs negative)3.155 (2.584-3.851)0.000
CA125 (positive vs negative)2.521 (2.067-3.074)0.000
CA19-9 (positive vs negative)3.489 (2.847-4.276)0.000
Multivariate analysis
Age (< 65 vs ≥ 65)1.225 (0.999-1.501)0.052
Clinical stage
I1 (Reference)
II2.102 (1.248-3.540)0.005
III4.860 (2.988-7.907)0.000
Location
Cardia1 (Reference)
Gastric body1.531 (1.187-1.976)0.051
Antrum of stomach1.092 (0.847-1.406)0.498
Differentiation (well, high and medium vs moderate to low and poor)1.212 (0.940-1.564)0.139
Borrmann type (III vs other)0.873 (0.688-1.108)0.265
Size (< 5 vs ≥ 5)1.269 (1.020-1.578)0.032
AFP (positive vs negative)1.728 (1.359-2.198)0.000
CEA (positive vs negative)2.037 (1.646-2.522)0.000
CA125 (positive vs negative)1.739 (1.416-2.135)0.000
CA19-9 (positive vs negative)1.910 (1.535-2.377)0.000