Predictive value of tumor-infiltrating lymphocytes for neoadjuvant therapy response in triple-negative breast cancer: A systematic review and meta-analysis

Figure 3 Funnel plot illustrating the correlation between tumor-infiltrating lymphocyte levels and the pathological complete response rate in studies investigating neoadjuvant therapy in triple-negative breast cancer patients. A: An asymmetric funnel plot and Egger’s test P value (P = 0.001) less than 0.05 suggested potential publication bias in the included studies of overall meta-analysis; B: Trim-and-fill method showed that there was no significant asymmetry in the trimmed funnel plot and still significant overall meta-analytical effect size after adjusting for publication bias, suggesting that there was limited or insignificant publication bias.