Parthenolide enhances the metronomic chemotherapy effect of cyclophosphamide in lung cancer by inhibiting the NF-kB signaling pathway

Figure 4 Effects of parthenolide combined with cyclophosphamide on tissue morphology and macrophage infiltration of transplanted tumors. A: Hematoxylin and eosin staining; B: CD31 staining and statistical results of tumor vascular density; C: F4/80 and CD206 staining in tumor tissues as well as comparison of F4/80 and CD206 positive cell proportion. Magnification: 200 ×. n = 10; ^aP < 0.05; ^bP < 0.01; ^cP < 0.001; ^dP < 0.0001; NS: Not significant. Con: Control; PTL: Parthenolide; CTX: Cyclophosphamide; HE: Hematoxylin and eosin staining.